In Reply Drs Vidale and Bono and Dr Sciascia and colleagues suggest that the factors responsible for the high long-term mortality after stroke in young adults should be investigated. However, the aim of our study was to provide estimates of mortality for selected subgroups of stroke (transient ischemic attack, ischemic stroke, and intracerebral hemorrhage). High-risk groups within this population can be identified.
One of the factors that Vidale and Bono propose is clinical severity and disability. However, a previous study1 did not find an association between stroke severity and 5-year mortality after stroke in young adults, whereas another study2 showed an association between stroke severity and a combination of unfavorable outcome and death within 3 months after stroke in young adults.
Rutten-Jacobs LCA, van Dijk EJ, de Leeuw F. Long-term Follow-up of Young Adults With Stroke—Reply. JAMA. 2013;310(3):321–322. doi:10.1001/jama.2013.7948