To the Editor: The article by Dr
D'Amico and colleagues1 presents a relatively unbiased
analysis of biochemical outcome in a series of 1872 patients treated
with several different types of local therapy at 2 institutions. Even
though the study is retrospective, the lack of randomized trials
addressing this issue gives this work greater significance in helping
to define the optimal management of this disease.
Vicini FA, Kestin LL, Martinez AA. Prostatectomy, External Beam Radiation Therapy, or Brachytherapy for Localized Prostate Cancer. JAMA. 1999;281(17):1583-1586. doi:10-1001/pubs.JAMA-ISSN-0098-7484-281-17-jbk0505