L. R., a boy, aged 4½, whose parents were healthy and had two heatlhy children, and whose past history was negative, was admitted to the Children's Hospital, Boston, Feb. 16, 1921, showing general weakness, loss of knee jerks, and redness and peeling of the finger tips and toes, which at first glance seemed on the one hand to be a case of multiple neuritis, and on the other, a postscarlatina case. I looked up the cases of acrodynia reported by Weston1 and by Byfield,2 and the case fits in so well with that disease that I believe it is worth reporting.
Six weeks before admission, he seemed tired, and after playing for half an hour, would want to sit down and rest. He did not want to eat anything, was constipated, and did not sleep well. His mother noticed that his hands and feet were cold. He could walk.
Emerson PW. A CASE OF ACRODYNIA. JAMA. 1921;77(4):285–286. doi:10.1001/jama.1921.92630290001014a