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Current Concepts in Cancer—NO 2
January 4, 1965

Radical Surgery

JAMA. 1965;191(1):26-27. doi:10.1001/jama.1965.03080010032007

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The perennial flare-up between radiotherapists and surgeons in relation to the use of either method in the treatment of neoplastic disease has, in recent years, led not only to more confusion, but, at the same time, to some clarification of our concepts of the entity called Hodgkin's disease. The recent literature is such a welter of contradictions, scattered misquotes, and almost vituperative protagonism, that the author is tempted to confine his references and bibliography to Lewis Carroll's Alice in Wonderland. To paraphrase:

"The time has come," the walrus said,

"To talk of Sternberg cells,

Of nodes—and drugs and surgery,

Of death—and tolling bells.

And why these points are boiling hot

And whether rays make well."

The current renewed interest in Hodgkin's disease is due to two observations: (1) that the course of the disease can be modified greatly by the use of alkylating agents and other forms of chemotherapy, and