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Members of families with a history of certain cancers may miss out on potentially life-saving screening tests or treatment because many forego genetic testing to estimate their cancer risk.
Investigators from cancer centers throughout France analyzed data from patients who were referred between 2003 and 2011 because of an increased risk of breast or colorectal cancer. Testing to detect mutations in the BRCA1 and BRCA2 genes that increase risks for breast and ovarian cancers had more than tripled. But records showed only a modest increase in testing to detect genetic mutations linked with Lynch syndrome, which increases the risk of colorectal and other cancers.
From JAMA’s Daily News Site. JAMA. 2013;310(7):681. doi:10.1001/jama.2013.194337