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October 12, 2011

Vitamin D Supplementation for Cardiovascular Disease Prevention

Author Affiliations

Author Affiliations: Mid America Heart and Vascular Institute, Kansas City, Missouri (Dr O[rsquo]Keefe) (jokeefe@saint-lukes.org); John Ochsner Heart and Vascular Institute, New Orleans, Louisiana (Dr Lavie); and Department of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, Massachusetts (Dr Holick).

JAMA. 2011;306(14):1546-1548. doi:10.1001/jama.2011.1465

To the Editor: We take issue with Drs Shapses and Manson1 in their defense of the Institute of Medicine (IOM) recommendations that the daily allowance of vitamin D be 600 IU per day for individuals aged 1 to 70 years and 800 IU per day for those older than 70 years. A recent study using the National Health and Nutrition Examination Survey 2005-2006 analyzed vitamin D levels in 4495 adults and found vitamin D deficiency, defined as a serum 25-hydroxyvitamin D level 20 ng/mL or less, in 42% of the overall population, 82% of black individuals, and 69% of Hispanic individuals.2