Some statins interact with certain antibiotics, putting older adults who take both at increased risk for hospitalization and death.
An analysis of medical records from about 73 000 older adults showed that taking statins and clarithromycin or erythromycin increased the risk of being hospitalized with rhabdomyolysis by about 0.02%. Either combination also increased the risk of death from any cause by 0.25%. The figures translate to 1 additional hospitalization for every 5870 patients co-prescribed a statin and clarithromycin or erythromycin and 1 additional death for every 399 patients taking either combination of drugs.
From JAMA’s Daily News Site. JAMA. 2013;310(8):785. doi:10.1001/jama.2013.254573