[Skip to Content]
[Skip to Content Landing]
Views 806
Citations 0
Comment & Response
October NaN, 2013

Risks Associated With Opioid Use

Author Affiliations
  • 1Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania
JAMA. 2013;310(16):1737. doi:10.1001/jama.2013.277305

To the Editor Dr Dowell and colleagues1 discussed the recent increase in opioid-related deaths and attributed it primarily to increased opioid prescribing for chronic, nonmalignant pain. The authors stated that long-term opioid therapy ultimately leads to tolerance and this in turn triggers opioid dose escalation, which is the major risk factor for opioid overdose.

First Page Preview View Large
First page PDF preview
First page PDF preview