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News From the Centers for Disease Control and Prevention
October 23/30, 2013

Beware of MDR Bacteroides fragilis

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Copyright 2013 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2013;310(16):1668. doi:10.1001/jama.2013.279073

Clinicians have yet another type of multidrug-resistant (MDR) bacteria to put on the radar screen: MDR Bacteroides fragilis.

Bacteroides fragilis strains are obligate anaerobic bacteria that live in the human gut. They’re usually susceptible to metronidazole, carbapenems, and beta-lactam antibiotics, especially in the United States. But last May, a US resident in his 70s who recently had traveled to India was diagnosed with B fragilis infection that did not respond to treatment with several antibiotics, including metronidazole, imipenem, piperacillin/tazobactam, and clindamycin.

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