Do statins reduce rates of cardiovascular events when used for primary prevention?
When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.
Taylor FC, Huffman M, Ebrahim S. Statin Therapy for Primary Prevention of Cardiovascular Disease. JAMA. 2013;310(22):2451–2452. doi:10.1001/jama.2013.281348