December 13, 1913
The study of cancer has been approached from a number of directions, which, for the most part, have been determined by the previous experience of the persons engaged in cancer research. Pathologists have been responsible for the search for infective organisms; biologists have elaborated the investigation of specific types of cell proliferation in connection with neoplasms; physiologic chemists have sought for evidences of fundamental alterations in tissue metabolism. This competition among different lines of scientific endeavor has been wholesome and stimulating to the study of disease, as it has furnished various points of view which would probably never have become recognized had it not been for the highly practical considerations which called forth so much effort on the part of many workers.
Metabolism in Cancer. JAMA. 2013;310(22):2462. doi:10.1001/jama.2013.5458