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In Reply Dr Capurso compares our discussion of cancer terminology to myocardial infarction and stroke. However, unlike the example of a small, low-grade prostate cancer that is seen in the majority of men but rarely causes harm,1 myocardial infarction and stroke are indicative of a physiological and pathological process that, left untreated, has a high risk of morbidity or mortality. Thus, maintaining the nomenclature of myocardial infarction, for example, is important to determine treatment.
Esserman LJ, Thompson IM, Reid BJ. Changing the Terminology of Cancer—Reply. JAMA. 2014;311(2):203. doi:10.1001/jama.2013.283385