To the Editor Drs Ridker and Wilson1 proposed that statin guidelines formulate treatment recommendations through consideration of “… patient populations for whom clinical trials have demonstrated benefit.” They failed to provide a clear definition of benefit. The authors cited approximately 20 randomized clinical trials; however, the measures of benefit varied widely between some of these trials.
O’Sullivan C, Brown L. Formulation of Treatment Recommendations for Statins. JAMA. 2014;311(3):305. doi:10.1001/jama.2013.284440