The complexity of cancer genetics, layered on top of the complexity of the human genome itself, creates a daunting task for researchers seeking to decipher the genetic factors involved in tumorigenesis and cancer development. But a relatively new laboratory technique may make the job easier by allowing investigators to efficiently screen for genes that are essential for cancer cells' survival (Silva JM et al. Science. 2008;319:617-620; Schlabach MR et al. Science. 2008;319:620-624).
Hampton T. New Screening Tool Reveals Genes Essential for Cancer Cells’ Survival. JAMA. 2008;299(11):1247-1248. doi:10.1001/jama.299.11.1247