To the Editor: Rather than represent a lack of antimicrobial efficacy, the null results reported by Dr Williamson and colleagues1 in their trial of antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis more likely stem from inappropriate use of diagnostic criteria proposed by Berg and Carenfelt2 in a sample for which they were never intended.
Rosenfeld RM. Antibiotics and Nasal Steroids for Acute Sinusitis. JAMA. 2008;299(12):1422-1423. doi:10.1001/jama.299.12.1422-a