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Clinical Trials Update
January NaN, 2014

Gastroesophageal Reflux Symptoms Abate When Smoking Stops

JAMA. 2014;311(4):349. doi:10.1001/jama.2013.286076

Quitting smoking improved gastroesophageal reflux symptoms (GERS), but only in individuals of normal weight who used antireflux medications at least weekly, according a prospective study of the population of Nord-Trøndelag County, Norway (Ness-Jensen E et al. Am J Gastroenterol. doi:10.1038/ajg.2013.414 [published online December 10, 2013]). The investigators used data from 29 610 individuals who reported having GERS during both of 2 health surveys—from 1995 to 1997 and from 2006 to 2008. In the subset of respondents with severe GERS (1553 individuals), they examined GERS status among those who had quit smoking between the 2 survey periods, status among those who had sustained their smoking, and the association of symptoms with the usage of antireflux medications.

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