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Lab Reports
February 5, 2014

New Method Detects Genetic Defects in Egg Cells

JAMA. 2014;311(5):456. doi:10.1001/jama.2014.286

A new method for analyzing single immature egg cells, or oocytes, collected for in vitro fertilization can detect both chromosomal abnormalities and DNA sequence variations associated with genetic disorders, report researchers from China and the United States (Hou Y et al. Cell. 2013;155[7]:1492-1506). Unlike most currently available screening techniques, which cannot simultaneously detect both types of defects, the new approach is not invasive and does not require the removal of cells from a growing embryo.

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