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Health Agencies Update
June 25, 2008

Hospital-Acquired Infection

JAMA. 2008;299(24):2847. doi:10.1001/jama.299.24.2847-d

The number of patients with Clostridium difficile–associated disease more than doubled between 2000 and 2005 despite efforts to rein in such hospital-acquired infections, according to a recent report from the Agency for Healthcare Research and Quality.

Based on data from the Healthcare Cost and Utilization Project, the number of patients discharged with C difficile–associated disease rose from 139 000 in 2000 to more than 300 000 in 2005 ( This represents a more than 200% increase in such infections. Between 1993 and 2000, the number of infections rose from 85 700 to 139 000, a 74% increase in such cases.

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