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Lab Reports
August 6, 2008

Imaging the Genesis of HIV

JAMA. 2008;300(5):496. doi:10.1001/jama.300.5.496-b

A new study details the genesis of individual HIV virions, following their progress from initiation of assembly to budding and release (Jouvenet N et al. Nature. 10.1038/nature06998 [published online ahead of print May 25, 2008]).

Researchers at the Aaron Diamond AIDS Research Center and the Rockefeller University, both in New York City, used total internal reflection fluorescence microscopy to measure and analyze the assembly of proteins to form HIV-1 virions in infected cells, a feat that has not been possible with conventional techniques.

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