The malaria parasite produces a number of proteins that empower it to hijack and remodel human red blood cells, according to a new study (Maier AG et al. Cell. 2008;134:48-61).
A team led by researchers at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, disabled a large number of genes to identify proteins that are exported into Plasmodium falciparum–infected red blood cells and are involved in remodeling these cells.
Hampton T. Malaria Mechanism. JAMA. 2008;300(9):1016. doi:10.1001/jama.300.9.1016-a