[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.94.5. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Lab Reports
November 5, 2008

Alzheimer Disease Gene

JAMA. 2008;300(17):1989. doi:10.1001/jama.2008.531

Mice whose cells have only 1 copy of the “antideath gene” p73 develop degenerative brain disease, according to a recent study by investigators led by researchers at McGill University in Montreal, Quebec (Wetzel MK et al. Neuron. 2008;59[5]:708-721).

The findings may have relevance to humans because some patients with Alzheimer disease lack 1 copy of the p73 gene. Therefore, normal levels of the p73 protein may play an important role in protecting individuals against this disorder.

First Page Preview View Large
First page PDF preview
First page PDF preview
×