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The Medical Letter on Drugs and Therapeutics
February 26, 2014

Drugs for Urinary Tract Infections

JAMA. 2014;311(8):855-856. doi:10.1001/jama.2014.972

The most recent guidelines from the Infectious Diseases Society of America (IDSA) and its European counterpart on the choice of antimicrobials for treatment of uncomplicated urinary tract infections (UTIs) in non-pregnant women focus on the unnecessary use of fluoroquinolones to treat uropathogens that are increasingly becoming resistant to them.1 Resistance of Escherichia coli to ciprofloxacin in the US has increased from 3% in 2000 to 17.1% in 2010.2

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