In a Clinical Crossroads article published in February 2007,1 Richard S. Legro, MD, discussed the epidemiology, causes, diagnostic considerations of, and treatment options for polycystic ovary syndrome (PCOS). Ms R, an otherwise healthy 27-year-old woman, was diagnosed as having PCOS after experiencing weight gain, periods of amenorrhea lasting up to 4 months, and development of mild facial hair growth and acne. Although her blood work results were normal, her physician confirmed her diagnosis with an ultrasound that showed numerous small ovarian cysts. She subsequently began taking oral contraceptives, which regulated her menstrual cycle.
Mattson-DiCecca AA, Farag N, Reynolds EE. Update: A 27-Year-Old Woman With a Diagnosis of Polycystic Ovary Syndrome. JAMA. 2009;301(5):532. doi:10.1001/jama.2009.38