Researchers at Vanderbilt University Medical Center in Nashville, Tenn, are studying whether a new nasal spray may be an effective method of vaccinating children against influenza.
In a study of 19 children, researchers obtained nasal washes from those who received the vaccine or a placebo. The majority who received the vaccine had developed IgA antibodies to 3 strains of influenza virus, while most of those who received the placebo did not develop antibodies to the virus strains.
Voelker R. Flu Vaccine in Nasal Spray. JAMA. 1998;279(20):1599. doi:10.1001/jama.279.20.1599-JQU80002-3-1