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Lab Reports
May 6, 2009

Spinal Stimulation

JAMA. 2009;301(17):1758. doi:10.1001/jama.2009.570

Spinal stimulation produces meaningful improvements in locomotion in 2 different animal models of Parkinson disease, reported an international team of scientists.

Dopamine replacement is currently the primary therapy for Parkinson disease, but such therapy may become less effective over the long term. Deep brain stimulation, which involves delivering electric impulses through electrodes that are precisely positioned in the brain, also is used to alleviate locomotor symptoms. Now, a team of researchers has demonstrated that a less invasive technique, epidural stimulation of the dorsal columns, might be useful (Fuentes R et al. Science. 2009;323[5921]:1578-1582).

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