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Quick Uptakes
October 28, 1998

Errors Prompt New Warnings

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JAMA. 1998;280(16):1393. doi:10.1001/jama.280.16.1393-JQU80007-2-1

Repeated injuries and several deaths have prompted the Institute for Safe Medication Practices (ISMP) to issue special alerts on the use of lipid-based drugs and on the improper dilution of albumin.

The ISMP said medication errors continue to occur from confusion between lipid-based drugs and their conventional counterparts. The particular drug pairs named were lipid-based forms of amphotericin B (Abelcet, Amphotec, and Ambisome) and the conventional form for injection (generic and Fungizone); the pegylated liposomal form of doxorubicin (Doxil) and its conventional counterpart, doxorubicin hydrochloride (Adriamycin and Rubex); and a liposomal form of daunorubicin (DaunoXome, daunorubicin citrate liposomas) and conventional daunorubicin hydrochloride (Cerubidine).

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