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May 20, 2009

Treadmill Exercise or Resistance Training in Patients With Peripheral Arterial Disease

JAMA. 2009;301(19):1986-1987. doi:10.1001/jama.2009.649

To the Editor: Dr McDermott and colleagues1 reported the results of a randomized trial of treadmill exercise or resistance training in patients with peripheral arterial disease (PAD), a prevalent condition. I am interested in knowing what medications the participants were using. Drugs such as aspirin, cilostazol, pentoxifylline, and clopidogrel that are used for PAD could have altered the outcome of the study. There may be improved walking distances with both cilostazol and pentoxifylline in comparison with placebos.24

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