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Health Agencies Update
May 19, 1999

"Irish" Mystery Malady

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JAMA. 1999;281(19):1784. doi:10.1001/jama.281.19.1784-JHA90003-4-1

Some 17 years ago, British researchers described an Irish family with an unusual inherited malady, one that caused periodic episodes of high fever, severe abdominal, chest, or joint pain, and skin rash in the affected family members. Last month, the condition became somewhat less mysterious when researchers from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMSD) and the Royal London Hospital School of Medicine and Dentistry reported the discovery of gene mutations underlying "familial Hibernian fever" (Cell. 1999;97:133-144).

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