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February 24, 1999

Diabetes Risk

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JAMA. 1999;281(8):694. doi:10.1001/jama.281.8.694-JQU90000-4-1

The largest study of its kind to date shows that women with polycystic ovary syndrome (PCOS) are at increased risk for impaired glucose tolerance (IGT) and type 2 diabetes mellitus.

In last month's Journal of Clinical Endocrinology and Metabolism, researchers from Brigham and Women's Hospital in Boston and Pennsylvania State University College of Medicine in Hershey reported on a controlled study of 254 women with PCOS. The women were in two study groups—one in ethnically diverse New York City and another in a primarily white region of rural Pennsylvania. Overall, the researchers found that 31.1% of the women had IGT and 7.5% had undiagnosed diabetes.

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