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Comment & Response
March 12, 2014

Mortality in Patients With Hypovolemic Shock Treated With Colloids or Crystalloids

Author Affiliations
  • 1Service de Réanimation Médicale, GH Henri Mondor, Créteil, France
  • 2Department of Critical Care Medicine, National Institutes of Health Clinical Center, Bethesda, Maryland
JAMA. 2014;311(10):1068-1069. doi:10.1001/jama.2014.836

To the Editor Dr Annane and colleagues1 reported that 28-day mortality (primary end point) did not significantly differ between patients with hypovolemic shock assigned to various colloid fluid therapies (69% of whom received hydroxyethyl starch) vs crystalloid fluid therapies. They also reported that 90-day mortality (one of many secondary end points) was significantly higher with crystalloids.

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