Author Affiliations: Department of Medicine, Rush University School of Medicine, Chicago, Illinois (Dr McNutt); Division of Hematology/Oncology and Comprehensive Cancer Center, University of Alabama, Birmingham (Dr Pasche); Drs McNutt and Pasche are Contributing Editors and Dr Fontanarosa (email@example.com) is Executive Deputy Editor, JAMA.
Cancer is perhaps the most dreaded diagnosis for patients, the most concerning for their families, and at times, the most challenging for physicians. Cancer is a leading cause of death worldwide, estimated to account for nearly 7 million deaths annually.1 In 2008, an estimated 12 million new cases of cancer were diagnosed and an estimated 25 million persons were alive with cancer.1 In the United States, cancer is the second leading cause of death, with approximately 270 000 cancer deaths among US women and 292 000 cancer deaths among US men projected to occur in 2009.2 The lifetime risk of developing cancer (excluding basal/squamous skin cancers and some in situ cancers) is estimated at approximately 1 in 3 for US women and 1 in 2 for US men.2 In addition, many cancers are associated with significant morbidity, often taking a devastating toll on physical functioning, quality of life, and emotional well-being.
McNutt RA, Pasche B, Fontanarosa PB. A Theme Issue on CancerCall for Papers. JAMA. 2009;302(3):327. doi:10.1001/jama.2009.1065