Harriet S.MeyerMD, Contributing EditorJonathan D.EldredgeMLS, PhD, Journal Review EditorRobertHoganMD, adviser for new media
Manic-depressive illness, or bipolar affective disorder, is mysterious and intangible. It changes how a person thinks and feels, yet there is no fever, no characteristic laboratory findings, and nothing to measure. Often, those affected do not realize that they are ill; family and friends are perplexed, scared, or enraged by their behavior. In the absence of tissue to send to the pathologist, autobiographical accounts of the illness can help us to understand the bipolar disorder.
PsychiatryBreakdown: A Personal Crisis and a Medical Dilemma. JAMA. 1999;282(15):1487. doi:10.1001/jama.282.15.1487-JBK1020-4-1