Nottingham, England—Men previously thought sterile are being given the chance of fatherhood thanks to a new two-step in vitro fertilization (IVF) technique developed at a clinic here. To date, the laboratory mating of sperm recovered from supposedly infertile men and eggs from their hopeful partners has resulted in a quartet of mothers-to-be.
Simon Fishel, PhD, and colleagues at Centres for Assisted Reproduction (CARE) have discovered that traditional sperm analysis can miss tiny numbers of sperm in a semen sample. They have devised a method of extracting as few as one or two sperm from men whose samples previously showed a "no sperm" count. About one fourth of the men who were thought to be infertile and sought help at his clinic have had sperm successfully extracted, said Fishel.
Fitzpatrick M. New Technique Treats Male Infertility. JAMA. 1999;282(15):1414. doi:10.1001/jama.282.15.1414-JMN1020-4-1