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Medical News & Perspectives
October 20, 1999

New Technique Treats Male Infertility

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JAMA. 1999;282(15):1414. doi:10.1001/jama.282.15.1414-JMN1020-4-1

Nottingham, England—Men previously thought sterile are being given the chance of fatherhood thanks to a new two-step in vitro fertilization (IVF) technique developed at a clinic here. To date, the laboratory mating of sperm recovered from supposedly infertile men and eggs from their hopeful partners has resulted in a quartet of mothers-to-be.

Simon Fishel, PhD, and colleagues at Centres for Assisted Reproduction (CARE) have discovered that traditional sperm analysis can miss tiny numbers of sperm in a semen sample. They have devised a method of extracting as few as one or two sperm from men whose samples previously showed a "no sperm" count. About one fourth of the men who were thought to be infertile and sought help at his clinic have had sperm successfully extracted, said Fishel.

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