Washington—The possibility that some environmental chemical contaminants may interfere with endocrine system function and adversely affect human health should be investigated, concludes Hormonally Active Agents in the Environment, a new report from the National Research Council.
The agents involved include a wide variety of chemicals that mimic the actions of hormones. They include substances such as polychlorinated biphenyls (PCBs), 1,1-dichloro-2,2-bis(p-chlorophenyl)-ethylene (DDE), and polychlorinated dibenzofuran (PCDF). Exposure to these agents has been shown to have adverse reproductive and developmental effects in humans, wildlife, and laboratory animals.
Marwick C. Hormonally Active Agents Throughout the Environment. JAMA. 1999;282(8):722. doi:10.1001/jama.282.8.722-JMN0825-3-1