[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.163.65.30. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Quick Uptakes
May NaN, 2000

Chemotherapy Breath Test

Author Affiliations
 

Not Available

Not Available

JAMA. 2000;283(20):2646. doi:10.1001/jama.283.20.2646-JQU00003-4-1

A relatively simple breath test could prove to be lifesaving for some patients who receive cancer chemotherapy.

The test offers a new method of determining how rapidly patients metabolize docetaxel. In a study of 21 patients with cancer, researchers at the University of North Carolina at Chapel Hill first used several blood tests in a 24-hour period to determine how quickly the patients' livers cleared docetaxel. They then compared those findings with results from a breath test in which the researchers gave the patients a trace dose of erythromycin and measured the amount of carbon dioxide they exhaled. Rapid metabolizers of erythromycin exhale higher concentrations of carbon dioxide, and slow metabolizers exhale smaller amounts.

First Page Preview View Large
First page PDF preview
First page PDF preview
×