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The World in Medicine
October 11, 2000

Recessive Alzheimer Gene?

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JAMA. 2000;284(14):1777. doi:10.1001/jama.284.14.1777-JWM00008-2-1

An Arab community living in northern Israel has provided researchers with the first evidence that a recessive gene may be involved in the development of Alzheimer disease (AD).

In the September 12 issue of Neurology, researchers reported on a study of 821 elderly Arab residents in the rural Wadi Ara community. Of those aged 85 years and older, 61% had AD. In other populations, about 40% of people the same age have the illness. Similarly, 20% of those older than 65 years in Wadi Ara had AD vs about 10% in other populations.

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