Medical News & Perspectives
December 13, 2000

Anti-IgE Antibody May Help Treat Some Asthma Patients

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Copyright 2000 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2000American Medical Association

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JAMA. 2000;284(22):2859-2860. doi:10.1001/jama.284.22.2859-JMN1213-2-1

San Francisco—A paradigm shift has occurred over the past four decades in the treatment of asthma, a disease that during that time has increased in prevalence worldwide, particularly in urban areas of the industrialized West.

This change reflects a greater understanding of the pathophysiology of asthma. Once considered a disease of reversible bronchoconstriction, asthma is now considered a chronic inflammatory disease with the potential to cause irreversible deterioration of pulmonary function. Anti-inflammatory agents, inhaled corticosteroids (ICSs) chief among them, have become mainstays of asthma therapy.

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