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Books, Journals, New Media
January 3, 2001


Author Affiliations

Harriet S.MeyerMD, Contributing EditorDavid H.MorseMS, Journal Review EditorRobertHoganMD, adviser for new media


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JAMA. 2001;285(1):95-96. doi:10.1001/jama.285.1.95-JBK0103-2-1

To keep pace with modern advances in this field, the third edition of this classic reference text found it necessary to change the very definition of "vaccine":

Vaccines are proteins, polysaccharides, or nucleic acids of pathogens that are delivered to the immune system as single entities, as part of complex particles, or by living attenuated agents or vectors, thereby inducing specific responses that inactivate, destroy, or suppress the pathogen.

Furthermore, to accomplish their mission, Plotkin—the inventor of the rubella vaccine, former director of research for a vaccine manufacturer, and emeritus professor of pediatrics at University of Pennsylvania—and his new coeditor Orenstein, Director of the National Immunization Program at the Centers for Disease Control and Prevention in Atlanta, Ga, had to coax 96 true experts from America, Europe, Asia, and Australia to be coauthors.

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