The discovery by British researchers that genes other than the prion protein gene may play a role in the development of the human form of bovine spongiform encephalopathy (BSE) is prompting speculation that the disease may have a longer incubation period in some people. If this proves to be the case, estimates made last year based on the assumption that only 40% of the British population were at risk of developing the variant form of Creutzfeldt-Jakob disease (vCJD) would have be revised upward.
Stephenson J. More CJD Cases to Come?. JAMA. 2001;285(22):2847. doi:10.1001/jama.285.22.2847-JWM10005-2-1