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Books, Journals, New Media
October 17, 2001

HematopathologyNeoplastic Hematopathology

Author Affiliations

Harriet S.MeyerMD, Contributing EditorDavid H.MorseMS, Journal Review EditorRobertHoganMD, adviser for new media


Not Available


Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001American Medical Association


edited by Daniel M. Knowles, 2nd ed, 1984 pp, with illus, $249, ISBN 0-683-30246-9, Philadelphia, Penn, Lippincott Williams & Wilkins, 2001.

JAMA. 2001;286(15):1905-1906. doi:10.1001/jama.286.15.1905-JBK1017-3-1

This is an updated edition of the definitive textbook on hematopathology. The new edition is 334 pages longer but slightly thinner than the previous, 1992 edition. As noted in the preface, "knowledge of all facets of hematopathology (ie, morphology, immunology, and molecular biology) has continued to grow unabated."

The Revised European-American Lymphoma (REAL) Classification was introduced in 1994, and the recent World Health Organization Classification of Hematologic Malignancies has updated the REAL scheme. The cluster of differentiation (CD) antibodies included CD1 through CDw78 in 1992; in the new edition they extend to CD166. Moreover, the spectrum of CD antibodies useful in routinely processed, paraffin-embedded tissue has expanded significantly; most lymphomas can now be well characterized by immunohistochemistry using routinely processed, formalin-fixed sections. Similarly, the area of molecular diagnostics has expanded with the availability of more rapid polymerase chain reaction–based assays.

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