[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.161.241.199. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
The World in Medicine
December 12, 2001

Diagnosing Down Syndrome

Author Affiliations
 

Not Available

Not Available

JAMA. 2001;286(22):2801. doi:10.1001/jama.286.22.2801-JWM10013-2-1

Using ultrasonography to determine the presence or absence of a bone in the nose of fetuses aged 11 to 14 weeks could help improve the prenatal diagnosis of Down syndrome, according to researchers at King's College Hospital Medical School, London, and Ohio State University, Columbus.

Physicians diagnose Down syndrome with an invasive test—amniocentesis or chorionic villus sampling—in women considered to be at high risk after screening. In addition to maternal age as a risk factor, current screening methods include maternal blood testing during the second trimester and first-trimester fetal nuchal translucency scanning (which measures the accumulation of fluid at the back of the neck).

First Page Preview View Large
First page PDF preview
First page PDF preview
×