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JAMA 100 Years Ago
December 26, 2001

Corneal Disease Due to Smallpox.

Author Affiliations

JenniferReiling, Assistant Editor

JAMA. 2001;286(24):3055. doi:10.1001/jama.286.24.3055-JJY10044-2-1

DR. EDWARD JACKSON reported a case of a man aged 30 who came under his observation six weeks from the time he was taken with smallpox. Photophobia was intense; right eye was small; zone of pericorneal redness, gray infiltration of upper part of cornea. A few pustules extended into the infiltration. Vision equaled counting fingers at one foot, lids were hyperemic and swollen, left eye was normal. Applications of tannin and glycerin to everted lids and instillation of atrophic sulphate with bathing of the eye in very hot water, and the use of a solution of boric acid and holocain was employed. Within two days, pupil dilated fairly; eye was less sensitive. Two weeks later the vision improved to 4/60, and the eye appeared normal except for an intense haziness of the upper portion of the cornea.

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