Stephen J.LurieMD, PhD, Senior Editor
To the Editor: Dr Tice and colleagues1 concluded that grain fortification with folic acid and cyanocobalmin would be cost-effective, and even cost-saving, in reducing the risk of primary and secondary heart disease in the US population. However, 2 statements by the authors raise serious issues regarding the appropriate policy application of their findings.
Pogach L. Cost-effectiveness of Homocysteine-Lowering Therapy to Prevent Coronary Heart Disease. JAMA. 2002;287(2):191. doi:10.1001/jama.287.2.191-JLT0109-3-3