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Women who received radiation treatment for Wilms tumor in childhood are at increased risk for complications during pregnancy and should be carefully assessed and monitored by their obstetricians, said researchers from Rosewell Park Cancer Institute, Buffalo, NY.
The conclusions are part of a National Wilms Tumor Study Group (NWTSG) report published in the May 15 Journal of Clinical Oncology.
The NWTSG received reports on 427 pregnancies with duration of 20 weeks or more, including 409 liveborn singletons. The study was limited to pregnancies of patients or their partners who received no abdominal or only flank irradiation as part of their initial course of tumor treatment.
Mitka M. Pregnancy After Wilms Tumor. JAMA. 2002;287(24):3200. doi:10.1001/jama.287.24.3200-JQU20006-2-1