Although scientists have long suspected that the brain prevents weight gain by firing up a fat-burning furnace that turns excess calories into heat, little direct evidence existed to support this widely held hypothesis. Now, a new study in mice, conducted by researchers in the United States and Italy, has found that such a mechanism—known as diet-induced thermogenesis (DIT)—exists (Science. 2002;297:843-845).
Stephenson J. Pyre for Pounds. JAMA. 2002;288(10):1226. doi:10.1001/jama.288.10.1226-JWM20009-3-1