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November 20, 2002

Allocation Concealment in Clinical Trials

Author Affiliations

Stephen J.LurieMD, PhD, Senior Editor


Not Available

JAMA. 2002;288(19):2406. doi:10.1001/jama.288.19.2406-JLT1120-4-1

To the Editor: Dr Balk and colleagues1 found that randomized controlled trials (RCTs) with high scores for allocation concealment, double-blinding, and 22 other quality measures had similar results as low-quality trials, as defined by these indicators. However, the authors' ambitious efforts may have diluted the quality of some their assessments and hindered comparability with prior studies.

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