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Medical News & Perspectives
November 27, 2002

PET Theory Applied to Stroke Prevention

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JAMA. 2002;288(20):2531. doi:10.1001/jama.288.20.2531-JMN1127-4-1

Many physicians in the 1970s believed carotid artery bypass surgery provided benefit to patients at risk of having a first or recurrent stroke. But a large international clinical trial discredited the theory, and the procedure essentially disappeared from operating rooms in the United States.

Today some researchers think they have the imaging technology to identify a subset of patients with stroke whose response to medical treatment—anticoagulants or antiplatelet agents—is poor (subsequent stroke rate of 25% to 50% within 2 years) and who may benefit from bypass surgery.

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