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The World in Medicine
August 14, 2002

Hidden Plaque Ruptures

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JAMA. 2002;288(6):689. doi:10.1001/jama.288.6.689-JWM20008-2-1

Nearly 80% of patients recovering from a first myocardial infarction or other acute coronary syndrome (ACS) event have hidden plaque ruptures some distance away from the clot that caused the episode, according to a new study by French researchers. The investigators say that the finding supports the hypothesis that although a single lesion is clinically the culprit at the moment of an ACS event, the syndrome is associated with overall atherosclerotic plaque destabilization within the coronary arteries, a concept called pancoronaritis.

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