To the Editor: In their randomized controlled trial, Dr Garber and colleagues1 provided important information on the successful prevention of adolescent-onset depression using an evidence-based psychotherapy in high-risk adolescents. In their study, if a parent was currently depressed the adolescent did not benefit from treatment. This observation is consistent with other data suggesting that if a currently depressed mother is successfully treated, her children's symptoms are more likely to improve.
Weissman MM, Talati A. Depression in At-Risk Adolescents and Their Parents. JAMA. 2009;302(11):1167-1168. doi:10.1001/jama.2009.1329