To the Editor: The case-control study by Dr Li and colleagues1 found a significant association between obesity and overall survival among patients with pancreatic cancer. The article did not discuss chronic medication use by the participants, and it is possible that insulin, insulin secretagogues, metformin, and statin therapy might have confounded this relationship.
Goldstein MR, Mascitelli L, Pezzetta F. Obesity and Survival Among Patients With Pancreatic Cancer. JAMA. 2009;302(16):1752-1753. doi:10.1001/jama.2009.1510